22ª Matchday
| 16/04/21 | 16:00 | FK Lviv - Oleksandria | ||
| 17/04/21 | 13:00 | Minaj - FK Desna Chernihiv | ||
| 16:00 | Vorskla Poltava - Zorya Lugansk | |||
| 18:30 | Shakhtar Donetsk - Dynamo Kiev | |||
| 18/04/21 | 13:00 | Inhulets - Rukh Lviv | ||
| 16:00 | Il. Mariupol - Olimpik Donetsk | |||
| 18:30 | Kolos Kovalyovka - SK Dnipro-1 |
League Table: Premier League
| # | Team | MP | W | D | L | F | A | D | P | Last 5 matches | ||||||
| 1 | Dynamo Kiev | 21 | 16 | 4 | 1 | 45 | 14 | +31 | 52 | W | W | W | W | W | ||
| 2 | Shakhtar Donetsk | 20 | 12 | 6 | 2 | 44 | 15 | +29 | 42 | W | W | L | W | W | ||
| 3 | Zorya Lugansk | 20 | 11 | 5 | 4 | 35 | 14 | +21 | 38 | W | W | L | L | W | ||
| 4 | FK Desna Chernihiv | 21 | 10 | 6 | 5 | 33 | 21 | +12 | 36 | W | W | L | L | W | ||
| 5 | Vorskla Poltava | 21 | 9 | 7 | 5 | 29 | 18 | +11 | 34 | W | L | W | L | W | ||
| 6 | Kolos Kovalyovka | 21 | 8 | 9 | 4 | 28 | 20 | +8 | 33 | W | D | W | W | D | ||
| 7 | Oleksandria | 21 | 7 | 5 | 9 | 28 | 28 | +0 | 26 | L | L | L | W | D | ||
| 8 | SK Dnipro-1 | 21 | 7 | 4 | 10 | 30 | 33 | -3 | 25 | L | W | W | W | D | ||
| 9 | Il. Mariupol | 21 | 5 | 6 | 10 | 21 | 34 | -13 | 21 | L | W | D | L | L | ||
| 10 | Inhulets | 20 | 3 | 10 | 7 | 20 | 30 | -10 | 19 | L | L | W | W | D | ||
| 11 | Olimpik Donetsk | 20 | 5 | 2 | 13 | 23 | 37 | -14 | 17 | L | L | L | L | L | ||
| 12 | Rukh Lviv | 20 | 3 | 7 | 10 | 17 | 36 | -19 | 16 | W | L | L | L | W | ||
| 13 | Minaj | 20 | 3 | 6 | 11 | 12 | 35 | -23 | 15 | L | D | D | L | L | ||
| 14 | FK Lviv | 19 | 4 | 3 | 12 | 16 | 46 | -30 | 15 | L | L | W | L | L | ||
