21ª Matchday
| 22/04/21 | 20:00 | Ajax Amsterdam - FC Utrecht |
30ª Matchday
| 23/04/21 | 20:00 | Willem II Tilburg - RKC Waalwijk | ||
| 24/04/21 | 16:30 | SC Heerenveen - FC Zwolle | ||
| 18:45 | Sparta Rotterdam - VVV Venlo | |||
| 20:00 | PSV Eindhoven - FC Groningen | |||
| 25/04/21 | 12:15 | FC Emmen - Heracles Almelo | ||
| 14:30 | ADO Den Haag - Fortuna Sittard | |||
| 16:45 | Feyenoord Rotterdam - Vitesse Arnhem | |||
| FC Twente Enschede - FC Utrecht | ||||
| 20:00 | Ajax Amsterdam - AZ Alkmaar |
League Table: Eredivisie
| # | Team | MP | W | D | L | F | A | D | P | Last 5 matches | ||||||
| 1 | Ajax Amsterdam | 28 | 23 | 3 | 2 | 86 | 20 | +66 | 72 | W | W | W | W | W | ||
| 2 | PSV Eindhoven | 29 | 18 | 7 | 4 | 64 | 30 | +34 | 61 | W | W | L | D | W | ||
| 3 | AZ Alkmaar | 29 | 18 | 7 | 4 | 66 | 38 | +28 | 61 | W | W | W | W | L | ||
| 4 | Vitesse Arnhem | 29 | 17 | 5 | 7 | 46 | 28 | +18 | 56 | D | W | D | W | W | ||
| 5 | Feyenoord Rotterdam | 29 | 15 | 9 | 5 | 58 | 29 | +29 | 54 | W | W | D | D | W | ||
| 6 | FC Groningen | 29 | 13 | 7 | 9 | 35 | 33 | +2 | 46 | L | W | L | D | L | ||
| 7 | FC Utrecht | 28 | 11 | 10 | 7 | 45 | 36 | +9 | 43 | L | W | W | L | W | ||
| 8 | Heracles Almelo | 29 | 11 | 6 | 12 | 35 | 43 | -8 | 39 | W | L | D | W | W | ||
| 9 | FC Twente Enschede | 29 | 9 | 10 | 10 | 42 | 40 | +2 | 37 | L | L | D | L | D | ||
| 10 | SC Heerenveen | 29 | 9 | 10 | 10 | 39 | 40 | -1 | 37 | W | L | D | L | W | ||
| 11 | Sparta Rotterdam | 29 | 9 | 7 | 13 | 40 | 46 | -6 | 34 | L | W | D | W | W | ||
| 12 | Fortuna Sittard | 29 | 10 | 4 | 15 | 40 | 52 | -12 | 34 | L | L | L | W | L | ||
| 13 | FC Zwolle | 29 | 7 | 11 | 11 | 38 | 46 | -8 | 32 | W | L | W | L | L | ||
| 14 | RKC Waalwijk | 29 | 6 | 8 | 15 | 27 | 44 | -17 | 26 | L | L | W | L | L | ||
| 15 | Willem II Tilburg | 29 | 5 | 7 | 17 | 31 | 61 | -30 | 22 | L | L | D | W | D | ||
| 16 | VVV Venlo | 29 | 6 | 4 | 19 | 39 | 75 | -36 | 22 | L | L | L | L | L | ||
| 17 | FC Emmen | 29 | 4 | 9 | 16 | 30 | 58 | -28 | 21 | W | W | D | D | D | ||
| 18 | ADO Den Haag | 29 | 2 | 10 | 17 | 22 | 64 | -42 | 16 | D | L | L | L | L | ||
