25ª Matchday
| 23/01/21 | 14:00 | Exeter City - Stevenage FC | ||
| Scunthorpe Utd - Grimsby | ||||
| 16:00 | Cambridge Utd - Bradford City | |||
| Carlisle Utd - Forest Green Rovers | ||||
| Morecambe FC - Colchester United FC | ||||
| Oldham Athletic - Newport County | ||||
| Port Vale - Walsall FC | ||||
| Southend United - Mansfield Town | ||||
| Tranmere Rovers - Bolton | ||||
| Cheltenham Town - Barrow FC | ||||
| 02/02/21 | 20:00 | Crawley Town - Leyton Orient |
26ª Matchday
| 23/01/21 | 16:00 | Leyton Orient - Forest Green Rovers | ||
| 26/01/21 | 19:00 | Exeter City - Morecambe FC | ||
| 20:00 | Cheltenham Town - Oldham Athletic | |||
| Mansfield Town - Bolton | ||||
| Newport County - Carlisle Utd | ||||
| Salford City - Cambridge Utd | ||||
| Scunthorpe Utd - Port Vale | ||||
| Southend United - Bradford City | ||||
| Stevenage FC - Colchester United FC | ||||
| Barrow FC - Grimsby | ||||
| Tranmere Rovers - Harrogate Town | ||||
| 16/03/21 | 20:00 | Crawley Town - Walsall FC |
League Table: League Two
| # | Team | MP | W | D | L | F | A | D | P | Last 5 matches | ||||||
| 1 | Cambridge Utd | 24 | 12 | 5 | 7 | 38 | 23 | +15 | 41 | W | D | W | W | L | ||
| 2 | Newport County | 22 | 11 | 7 | 4 | 32 | 22 | +10 | 40 | D | D | D | L | D | ||
| 3 | Carlisle Utd | 21 | 12 | 3 | 6 | 32 | 20 | +12 | 39 | W | D | L | W | W | ||
| 4 | Salford City | 24 | 10 | 8 | 6 | 31 | 19 | +12 | 38 | D | D | W | L | L | ||
| 5 | Forest Green Rovers | 23 | 10 | 8 | 5 | 30 | 22 | +8 | 38 | L | D | L | D | W | ||
| 6 | Cheltenham Town | 23 | 10 | 7 | 6 | 32 | 23 | +9 | 37 | D | D | D | D | L | ||
| 7 | Leyton Orient | 23 | 11 | 3 | 9 | 34 | 26 | +8 | 36 | W | W | W | L | L | ||
| 8 | Morecambe FC | 22 | 10 | 5 | 7 | 28 | 33 | -5 | 35 | D | L | W | W | W | ||
| 9 | Crawley Town | 22 | 9 | 7 | 6 | 34 | 28 | +6 | 34 | W | W | D | W | D | ||
| 10 | Exeter City | 21 | 8 | 9 | 4 | 41 | 27 | +14 | 33 | D | D | D | L | W | ||
| 11 | Tranmere Rovers | 22 | 9 | 5 | 8 | 26 | 27 | -1 | 32 | W | D | D | L | W | ||
| 12 | Walsall FC | 24 | 7 | 11 | 6 | 29 | 32 | -3 | 32 | D | D | L | L | L | ||
| 13 | Colchester United FC | 22 | 7 | 9 | 6 | 28 | 30 | -2 | 30 | D | D | L | L | L | ||
| 14 | Mansfield Town | 23 | 6 | 11 | 6 | 31 | 30 | +1 | 29 | W | W | W | W | D | ||
| 15 | Port Vale | 24 | 8 | 5 | 11 | 33 | 34 | -1 | 29 | D | W | L | D | L | ||
| 16 | Oldham Athletic | 23 | 8 | 4 | 11 | 36 | 41 | -5 | 28 | D | L | D | L | W | ||
| 17 | Bolton | 23 | 7 | 7 | 9 | 27 | 35 | -8 | 28 | D | D | L | D | L | ||
| 18 | Harrogate Town | 23 | 7 | 6 | 10 | 24 | 28 | -4 | 27 | D | D | L | W | L | ||
| 19 | Bradford City | 21 | 6 | 6 | 9 | 20 | 25 | -5 | 24 | D | W | W | W | D | ||
| 20 | Barrow FC | 23 | 5 | 8 | 10 | 30 | 32 | -2 | 23 | W | L | D | W | W | ||
| 21 | Scunthorpe Utd | 23 | 7 | 2 | 14 | 22 | 34 | -12 | 23 | L | L | L | W | L | ||
| 22 | Stevenage FC | 21 | 4 | 9 | 8 | 16 | 22 | -6 | 21 | D | W | W | D | L | ||
| 23 | Grimsby | 24 | 5 | 6 | 13 | 19 | 40 | -21 | 21 | D | L | L | D | L | ||
| 24 | Southend United | 23 | 5 | 5 | 13 | 15 | 35 | -20 | 20 | L | D | W | L | W | ||
